Search results for "Resected Bone Specimen"

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CD34 and CD105 Microvessels in Resected Bone Specimen May Implicate Wound Healing in MRONJ

2021

Clinical treatment outcome of MRONJ (medication-related osteonecrosis of the jaw) surgery despite radical osseous removal and primary closure healing still shows differences in terms of outcome and disease recurrence. The study aims to assess the rate of angiogenesis of MRONJ lesions in order to understand the impact of angiogenesis and neoangiogenesis status on MRONJ surgical treatment outcome. This is the first study correlating microvessel density with prognosis in MRONJ surgically-treated patients. The immunohistochemical expression of CD34 and CD105 in MRONJ specimens obtained from surgically-treated patients was evaluated. The most vascularized areas detected by CD34 and CD105 were se…

medicine.medical_specialtyAngiogenesisHealth Toxicology and Mutagenesissurgical treatmentTreatment outcomeCD34MRONJArticleangiogenesismedicineHumansmedication-related osteonecrosis of the jawRadical surgeryRetrospective StudiesMicrovesselResected Bone SpecimenWound Healingbusiness.industryRPublic Health Environmental and Occupational HealthEndoglinmedicine.diseaseSurgeryCD105CohortMicrovesselstreatment outcomeMedicineBisphosphonate-Associated Osteonecrosis of the JawCD34Osteonecrosis of the jawWound healingbusinessInternational Journal of Environmental Research and Public Health
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